Efficacy analysis after surgical treatment for gastric cancer with synchronous hepatic metastases
10.3969/j.issn.1009-9905.2017.02.005
- VernacularTitle:胃癌同时性肝转移的外科治疗
- Author:
Cheng ZHANG
;
Peng ZHANG
;
Lei CHEN
;
Yi LIU
;
Shanglei NING
;
Yunfei XU
;
Zhaochen LIU
;
Yuxin CHEN
- Keywords:
Gastric neoplasms;
Hepatic metastases;
Surgical treatment
- From:
Chinese Journal of Current Advances in General Surgery
2017;20(2):96-99
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To clarify the indications and efficacy after simultaneous surgical treatment in gastric cancer patients with synchronous hepatic metastases (GCHM).Methods:A total of 21 GCHM patients who underwent D2 gastrectomy with R0 hepatic resection (11 cases) or non-R0 hepatic resection (10 cases) from March 2004 to April 2016 were analyzed retrospectively.The clinicopathological characteristics and survival were compared between the two groups.Results:Cumulative survival rate was improved in R0 hepatic resection group compared with non-R0 hepatic resection group:1-year (54.5％ vs 48.0％),2-year(27.3％ vs 0％),and 5-year(27.3％ vs 0％,P=0.044).The median survival time in R0 hepatic resection group and non-R0 hepatic resection group were 16.2 and 5.9 months (P=0.008).Univariate analysis revealed that Bormann's classification (P=0.010) and state of regional lymph node (P=0.004) were significant predictive factors regarding cumulative survival rate.However,there was no significant prognostic factor (P=0.031) in multivariate analysis might partly owing to interaction among them and/or a small number of patients.Conclusion:Multidisciplinary treatments based on R0 hepatic resection combined with D2 gastrectomy could improve survival in selected GCHM patients.
