Diagnostic and predictive value of hsCRP and CysC levels for acute coronary syndrome in aged patients

VernacularTitle:hsCRP、CysC水平对老年急性冠脉综合征诊断和病情预测的价值
Author: Jiangqiao HU ; Lifen SONG ; Shiying XU ; Bo JIA
Keywords: Acute coronary syndrome; C-reactive protein; Cysteine proteinase inhibitors
From: Chinese Journal of cardiovascular Rehabilitation Medicine 2017;26(2):165-167
CountryChina
Language:Chinese
Abstract: Objective: To study diagnostic and predictive value of levels of high sensitive C reactive protein (hsCRP) and cystatin C (CysC) for acute coronary syndrome (ACS) in aged patients.Methods: A total of 60 ACS patients (ACS group) treated in our hospital and 60 healthy subjects (healthy control group) undergoing physical examination during Dec 2013 to Sep 2015 were randomly selected.Serum levels of hsCRP and CysC, and abnormal rates of hsCRP and CysC were measured and compared between two groups.Results: Compared with healthy control group, there were significant rise in serum levels of hsCRP[(3.02±1.13) mg/L vs.(7.95±2.38) mg/L]and CysC[(0.75±0.11) μg/ml vs.(1.35±0.43) μg/ml], and abnormal rates of hsCRP (0 vs.13.33%) and CysC (0 vs.11.67%) in ACS group, P<0.01 all.Conclusion: Serum hsCRP and CysC level measurements can effectively predict and assess occurrence, development and prognosis of disease in ACS patients, and provide clinical valid evidence for its diagnosis, prevention and treatment.