Prospective study on central line-associated bloodstream infection among critically ill children in 2012-2015
10.3969/j.issn.1671-9638.2017.04.010
- VernacularTitle:2012-2015年重症儿童中心静脉导管相关血流感染前瞻性研究
- Author:
Danyang ZHAO
;
Qiaozhi GUO
;
Minxiong SITU
;
Jinhua LIAO
;
Suiping ZHANG
- Keywords:
central line-associated bloodstream infection;
intensive care unit;
pediatric intensive care unit;
neonatal intensive care unit;
healthcare-associated infection
- From:
Chinese Journal of Infection Control
2017;16(4):330-333
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the incidence of central line-associated bloodstream infection(CLABSI) among critically ill children, and provide basis for making preventive and control measures.Methods Prospective surveillance was performed to monitor CLABSI among children (including neonates) with central lines in 7 children's intensive care units(ICUs) from January 2012 to December 2015.Results Of 37 712 hospitalized patients, the overall length of hospital stay were 268 531 days, the overall central line-day was 57 639, utilization rate of central line was 21.46%;126 patients had CLABSI, CLABSI rate per 1 000 central line-days was 2.19, there was no significant difference in the CLABSI rate among each year(P>0.05);CLABSI rate in the third quarter was higher than that in other quarters(all P<0.05,compared with the first quarter,RR[95%CI]=1.98[1.20, 3.29]);CLABSI rates were different among different types of ICUs, surgical neonatal ICU (SNICU)(6.12/1 000 central line-days) was higher than other types of ICUs (all P<0.05, compared with pediatric ICUs[PICUs], RR[95%CI]=3.02[1.51-6.04]).126 patients with CLABSI were isolated 139 strains of pathogenic bacteria, the main pathogens were Klebsiella pneumoniae (20.86%) and Staphylococcus epidermidis (15.83%).Conclusion Critically ill children in SNICU are high risk population of CLABSI infection, intensified intervention measures should be developed for the department , so as to reduce CLABSI effectively.
