Value of white blood cell count, C-reactive protein combined with respiratory pathogen antibody in the early diagnosis of pneumonia in children
10.3969/j.issn.1005-1678.2017.04.137
- VernacularTitle:白细胞计数、C反应蛋白联合呼吸道病原体抗体检测在小儿肺炎的早期诊断价值
- Author:
Yanong FU
- Keywords:
white blood cell count;
C-reactive protein;
children with pneumonia
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):416-418
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of procalcitonin(PCT),C-reactive protein(CRP)and white blood cell count(WBC)in children with different pathogenic infectious diseases diagnostic value.Methods 1300 cases of hospitalized pneumonia fromJanuary 2013 to January 2016in our hospital were selected,and the CRP,WBC,PCT and pathogens were examined and compared.Results The positive rate of CRP was 13.53％,among the 1 300 cases,the number of CRP positive was the highest among the <1 year old group,the positive cases of MP-IgM,CP-IgM and RSV-IgM were mainly in the one to three years group,the expression of FLUA-IgM in children aged <1 and >5 years old in the group,and there was no significant difference between the two groups.The levels of serum PCT,CRP and WBC in bacterial infection group were significantly higher than those in virus infection group,the level of CRP in mycoplasma pneumoniae infection group was significantly higher than that in virus infection group,the levels of PCT and WBC in patients with bacterial infection were significantly higher than those in Mycoplasma infection group,the difference was statistically significant(P<0.05).There was no significant difference in CRP level between the two groups.The sensitivity and specificity of CRP> 0.05ng/mL,CRP> 6mg/L and WBC>10×109/L were 91.07％and 90.78％respectively.The positive predictive value was 87.95％,negative predictive value of 90.78％,compared to CRP and WBC diagnosis of sensitivity,specificity were significantly increased.Conclusion When the clinical diagnosis of infection in children can be diagnosed,the first application of WBC for testing,to be initially screening,followed by CRP and pathogen detection of the disease to conduct a comprehensive assessment and identification.
