Progress in Drug Treatment for Renal Ischemic Reperfusion Injury
- VernacularTitle:关于肾缺血再灌注损伤的药物治疗研究进展
- Author:
Guiling SONG
;
Lian YU
;
Jingbo HU
;
Yongzhong DU
- Keywords:
Ischemic reperfusion;
Caspase inhibitor;
Antioxidant agent;
P-selectin antagonist;
Research progress
- From:
China Pharmacist
2017;20(4):724-728
- CountryChina
- Language:Chinese
-
Abstract:
Renal ischemia reperfusion injury refers to the recovery failure of renal function induced by renal perfusion after ischemia,and resulting in a series of pathophysiological reactions.At present,there are no sovereign drugs for the treatment of renal ischemia reperfusion injury.Based on the pathophysiological characteristics of renal ischemia reperfusion injury and the latest research results at home and abroad,the article reviewed the research progress in the therapeutical drugs for renal ischemia reperfusion injury,including apoptotic protease inhibitors,P-selectin antagonists and antioxidants,which could provide reference for the effective intervention with the disease.
