Application of neoadjuvant chemoradiation therapy (nCRT) combined with laparoscopy in lower rectal reserving annus surgery
10.3969/j.issn.1009-9905.2017.02.004
- VernacularTitle:新辅助放化疗联合腹腔镜治疗低位直肠癌(保肛)临床疗效
- Author:
Qingtong ZHANG
;
Yali LIU
;
Xu ZHANG
;
Yongpeng WANG
;
Xiaofei YAN
;
Xingqi GUO
- Keywords:
Rectal neoplasms;
Laparoscopic surgery;
nCRT
- From:
Chinese Journal of Current Advances in General Surgery
2017;20(2):93-95
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To nvestigate the clinical curative effects and advantages on neoadjuvant chemoradiation therapy (nCRT) combined with laparoscopy in lower rectal reserving annus surgery.Methods:we make a retrospective analysis of 141 patients (nCRT group) who received nCRT combined with laparoscopic rectal cancer resection and of 141 cases simply received laparoscopic rectal cancer resection at the same period in the department of coiorectal surgery,Cancer Hospital of China Medical University、Liaoning Cancer Hospital&Institute,from December 2013 to December 2015.Results:Two groups in operation time,anus exhausting time,hospital stay time,number of harvest lymph node,incision infection rate,anastomotic leakage rate are not statistic differences;Two groups of reserving anus rate (136/141 vs 125/141,P＜0.05),intraoperating bleeding (54.8 ± 23.4ml vs 69.7 ± 29.1 mL,P＜0.05),positive rate of distance resection margin (0/141VS 2/141,P＜0.05),length of distance resection margin(2.35 ± 0.70VS2.02 ± 0.46,P＜0.05),local recurrence rate (2/141 VS 9/141,P＜0.05) are statistic differences.Conclusion:Neoadjuvant chemoradiation therapy(nCRT) combined with laparoscopic rectal resection can improve reserving anus rate and reduce local recurrence rate.
