Multidisciplinary team confirmed the simultaneous diagnosis of CLL and AML-M5
10.3969/j.issn.1000-8179.2017.07.464
- VernacularTitle:慢性淋巴细胞白血病合并急性髓系白血病多学科协作诊疗1例
- Author:
Qiaoyang NING
;
Hongliang YANG
;
Bing XIA
;
Liping BAI
;
Zeng CAO
;
Huijun WANG
;
Yizhuo ZHANG
;
Mingjian YOU
- Keywords:
chronic lymphocytic leukemia;
acute myeloid leukemia;
multidisciplinary team
- From:
Chinese Journal of Clinical Oncology
2017;44(7):337-343
- CountryChina
- Language:Chinese
-
Abstract:
A 54-year-old man diagnosed with chronic lymphocytic leukemia (CLL) was admitted in our department in June 2014. After one cycle of FC chemotherapy, a bone marrow examination revealed normalized lymphocyte count and another acute myeloid leuke-mia (AML)-M5 clone. The patient refused sequential treatment and only received follow-up examination. He had continuous hemato-logically stable disease and died of pulmonary infection on July 2015. After a multidisciplinary team discussion, we confirmed the si-multaneous diagnosis of CLL and AML-M5. Through this discussion,tumor second hit model,tumor evolution model,andtumor heterogeneitywere further defined.
