Depigmented Scrotal Extramammary Paget's Disease in a Patient with Rectal Cancer: A Case of Coincidental Double Primary Adenocarcinomas.
- Author:
Hei Sung KIM
1
;
Shin Taek OH
;
Si Yong LEE
Author Information
- Publication Type:Case Report
- Keywords: Extramammary Paget's disease; Depigmented patch; Concurrent rectal cancer; GCDFP-15; CK20
- MeSH: Adenocarcinoma*; Cytochrome P-450 CYP1A1; Humans; Keratin-20; Paget Disease, Extramammary*; Rectal Neoplasms*
- From:Annals of Dermatology 2006;18(1):18-20
- CountryRepublic of Korea
- Language:English
- Abstract: Extramammary Paget's disease (EMPD) typically presents as an eczematous, eroded or crusted plaque. Only a few cases with depigmentation have been reported. We herein report a patient with a depigmented scrotal patch as the sole finding of EMPD. Since he had concurrent rectal cancer, we stained the tissue with gross cystic disease fluid protein-15 (GCDFP-15) and cytokeratin 20 (CK20) in order to differentiate primary/secondary EMPD. This case represents coincidental primary EMPD and rectal cancer, of which the initial features of EMPD were unusual.
