Lipoprotein lipase gene polymorphisms and atherosclerosis
10.3760/cma.j.issn.1673-4165.2017.02.017
- VernacularTitle:脂蛋白脂酶基因多态性与动脉粥样硬化
- Author:
Xin CHEN
;
Yun XU
- Keywords:
Atherosclerosis;
Lipoprotein Lipase;
Polymorphism,Genetic;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2017;25(2):188-192
- CountryChina
- Language:Chinese
-
Abstract:
Lipoprotein lipase (LPL) is the rate-limiting enzyme for the hydrolysis of the triglyceride core of circulating triglyceride-rich lipoproteins.LPL can not only affect the lipoprotein level,but also play an important role in the development of atherosclerosis.LPL gene polymorphisms may affect LPL activity,and therefore have both pro-and anti-atherogenic effects.This article reviews the relationship between LPL gene polymorphism and atherosclerosis.
