Increased gastroesophageal junctioncompliance in patients with non-erosive reflux disease
- VernacularTitle:非糜烂性反流病患者胃食管交界顺应性增加
- Author:
Jixi LIU
;
Shuqiao ZHAO
;
Fang LIU
;
Xiaoou LI
;
Jingtao LI
- Keywords:
non-erosive reflux disease;
compliance;
gastroesophageal junction
- From:
Basic & Clinical Medicine
2017;37(5):714-717
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the biomechanical mechanism of non-erosive reflux disease(NERD).MethodsFrom October 4,2014 to September 30,2015,17 NERD patients and 17 healthy controls were recruited from the outpatients department of China-Japan Friendship Hospital.The cross-sectional area(CSA), intra-balloon pressure (IBP)and compliance(Δv/Δp)of each were measured by endoscopy in combination with EndoFlip.ResultsWith the increase of balloon volume,the compliance of gastroesophageal junction in NERD group was significantly higher than that of control group(P<0.01) while the cross sectional area and intra-balloon pressure were similar.Conclusions Increased compliance of the gastroesophageal junction may be involved in the pathogenesis of non-erosive reflux disease.
