Long Circulating Liposomes Delivery System in Diagnosis and Treatment of Tumor
10.3870/j.issn.1004-0781.2017.05.001
- VernacularTitle:长循环脂质体递送系统在肿瘤诊断和治疗中的应用
- Author:
Liang ZHANG
- Keywords:
Liposomes;
long circulating;
Diagnosis of target;
Treatment of tumor
- From:
Herald of Medicine
2017;36(5):463-468
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid development of modern medicine and pharmacy, the diagnosis and treatment of cancer have made great progress.However, cancer treatment is still a difficult and urgent problem in clinic, because the early detection is difficult for many tumors, the toxic and side effects are serious for drug therapy and treatment effect is poor.Long circulating liposomes delivery system based on nano-medicine are used for the diagnosis and treatment of tumors, which have brought new hope to cancer patients.After administration, long circulating liposomes are known for prolonging the circulation time, increasing the targeting accumulation in tumor, improving the effects of diagnosis and treatment and reducing the toxic and side effects of loading medicine or probe.In this paper, the advantages of long circulating liposome delivery system loaded with diagnostic probe or antitumor agent in targeting diagnosis and treatment of tumor are reviewed.