Diagnosis and management of adverse reaction due to botulinum toxin type A

VernacularTitle:A型肉毒毒素注射美容不良反应的评估及诊治
Author: Yanli WANG ; Jiali ZHU ; Jieling FAN ; Chunlian LI ; Yi HUANG ; Zhongliang JI
Keywords: Adverse reaction; Botulinum toxin type A; Cosmetic; Botulinum antitoxin
From: Chinese Journal of Medical Aesthetics and Cosmetology 2017;23(2):82-84
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical manifestation caused by local injections of botulinum toxin type A for cosmetic reason and the effect of antitoxin for adverse reaction.Methods Diagnosis and treatment process of 40 patients were retrospectively analyzed for adverse reactions due to botulinum toxin injections for beauty.Severe adverse reaction was assessed according to the patients clinical manifestation and the nervous system of physical assessment.The patients were given symptomatic treatment,observation or antitoxin therapy.Results Adverse reactions developed in 40 patients were mainly the nervous system abnormalities.Dyspnea developed in four cases.34 cases (85 ％) were given symptomatic treatment.4 cases (10 ％) were given botox treatment,and the patients were followed up for 1-3 months.The patients fully recovered to normal and did not leave any neurological sequelae.Conclusions The management of type A botulinum toxin injections should be strengthened.In case of poisoning,antitoxin therapy should be given as early as possible.