Leptin and soluble leptin receptor changes during pregnancy and as indicators of early screening for gestational diabetes
10.16571/j.cnki.1008-8199.2017.04.023
- VernacularTitle:瘦素与可溶性瘦素受体妊娠期变化及作为妊娠期糖尿病早期筛查指标的探索
- Author:
Rong LIN
- Keywords:
Leptin;
Soluble leptin receptor;
Gestational diabetes
- From:
Journal of Medical Postgraduates
2017;30(4):444-448
- CountryChina
- Language:Chinese
-
Abstract:
Leptin participates in the whole process of pregnancy.Soluble leptin receptor has close relationship with metabolic syndrome, type 2 diabetes.Leptin can two-way regulate insulin through different signal transduction pathways.Gestational diabetes influence maternal glucose metabolism and lipid metabolism.Soluble leptin receptors adjust the utilization rate and the concentration of leptin.It can increase the leptin sensitivity and indirectly involve in the body′s endocrine metabolism process.This article reviews the change of leptin and soluble leptin receptor during the pregnancy and the feasibility as early gestational diabetes screening index.
