Peroxiredoxin-2 is associated with cardiovascular risk factors in PCOS patients
10.3760/cma.j.issn.1008-6706.2017.11.003
- VernacularTitle:过氧化物还原酶2与多囊卵巢综合征患者发生心血管疾病危险因素的相关性研究
- Author:
Xiaomei ZHOU
;
Mingya SUN
- Keywords:
Oxidoreduction;
Cardiovascular disease;
Polycystic ovary syndrome
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(11):1609-1611
- CountryChina
- Language:Chinese
-
Abstract:
Objective PRDX-2 of the basic level in patients with PCOS,and its correlation with cardiovascular risk factors.Methods Collected 78 cases of PCOS patients for POCS group,at the same time,choose healthy check-up 40 cases for control group.Determination of plasma Peroxiredoxin-2,blood sugar,glycosylated hemoglobin,cholesterol,triglycerides,and other biochemical indicators.Results Peroxiredoxin-2 level in PCOS group are higher than the control group(F=26.03;P<0.05).Peroxiredoxin-2 and cardiovascular risk factors exist correlation,including systolic blood pressure (r=0.213),diastolic blood pressure (r=0.380),fasting blood glucose (r=0.308),glycosylated hemoglobin (r=0.303),cholesterol (r=0.190),triglyceride (r=0.276),LDL-C (r=0.484) were positively correlated,and CRP (r=0.227),HDL-C negative correlation (r=0.355).Conclusion Determination of Peroxiredoxin-2 level can be used as evaluation of patients with PCOS risk factors for cardiovascular disease.
