Research Progress in the Relationship Between GLP-1,GLP-2 and Colorectal Cancer

VernacularTitle:胰高血糖素样肽和结直肠癌关系的研究进展
Author: Zilong ZHANG
Keywords: Glucagon-like peptide; GLP-1R; GLP-2R; Colorectal cancer
From: Journal of Medical Postgraduates 2017;30(5):556-560
CountryChina
Language:Chinese
Abstract: Glucagon-like peptide (GLP-1, GLP-2) is a recently discovered intestinal epithelium-specific growth factor.This paper reviews the relationship between the origin, the secretion and the degradation of GLP-1 and GLP-2 and colorectal cancer.It provides basic data for the treatment of colorectal cancer and it′s useful to trade-offs the potential carcinogenesis between the applications of GLP-1, GLP-2 analogues with the inhibitors of degradation of the enzyme treatment.Developing the treatment of applying GLP-1 and GLP-2 into clinical practice has already become the new subject to carry out, which depends on the relevant basic and clinical experiments.