Distribution and antimicrobial resistance of pathogens causing bloodstream infection in a hospital in Sanya city
10.3969/j.issn.1671-9638.2017.03.008
- VernacularTitle:三亚某医院血流感染病原菌分布及耐药性
- Author:
Zhixia LI
;
Yufeng WANG
;
Li XU
;
Mei ZHAO
;
Xiaowei XING
- Keywords:
bloodstream infection;
blood culture;
pathogen;
drug resistance;
microbial
- From:
Chinese Journal of Infection Control
2017;16(3):221-224
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the distribution and antimicrobial resistance of pathogens isolated from blood culture in a hospital in Sanya city.Methods Blood culture specimens and antimicrobial susceptibility testing results in this hospital from January 2013 to December 2015 were analyzed retrospectively.Results A total of 356 isolates of pathogenic bacteria were isolated from 3 195 blood culture specimens,the positive rate was 11.14%,including 215(60.39%)gram-negative bacterial strains,122(34.27%) gram positive bacterial strains,and 19(5.34%) fungi strains.The top 3 gram negative bacteria were Escherichia coli (n =90,25.28%),Klebsiella pneumoniae (n =60,16.85%),and Burkholderia pseudomallei (n =24,6.74%);the most common gram positive bacteria were Staphylococcus aureus (n =42,11.80 %),coagulase-negative staphylococcus (n =38,10.67 %),and Streptococcus spp.(n =33,9.27 %).Resistance rates of Escherichia coli and Klebsiella pneumoniae to cefoperazone/sulbactam,amikacin,and carbapenems were all lower than 10.00%;resistance rates of Burkholderia pseudomallei to most antimicrobial agents were lower than 10.00%.There were no strains of main gram-positive bacteria that were found to be resistant to linezolid and vancomycin.Conclusion Gram-negative bacteria are the main pathogens causing bloodstream infection in this hospital in recent years,especially the isolation rate of Burkholderia pseudomallei is higher,which should arouse more attention in clinic.