Research progress of proton pump inhibitors on breast cancer
10.11904/j.issn.1002-3070.2017.02.017
- VernacularTitle:质子泵抑制剂在乳腺癌中的研究进展
- Author:
Yingqiang FU
- Keywords:
Proton pump inhibitors;
Breast cancer;
Omeprazole;
Pantoprazole
- From:
Practical Oncology Journal
2017;31(2):179-182
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,some studies have been shown that proton pump inhibitors(PPIs)not only play a role in digestive diseases,but it also has an important role in the treatment of breast cancer.PPIs,including omeprazole,pantoprazole,lansoprazole,esomeprazole,etc,improve the effect of breast cancer chemotherapy and induce breast cancer cell apoptosis by inhibiting intracellular proton excretion and increasing intracellular pH.This preview summarizes the study progress of PPIs in breast cancer and the potential application of PPIs in the treatment of breast cancer.
