Prognostic value of serum cardiac troponin Ⅰ in acute lung injury after living-donor liver transplantation for children with biliary atresia
10.3760/cma.j.issn.0254-1785.2016.10.002
- VernacularTitle:肌钙蛋白Ⅰ对胆道闭锁患儿亲属活体肝移植后急性肺损伤的预测价值
- Author:
Mingwei SHENG
;
Hongyin DU
;
Yiqi WENG
;
Rubin XU
;
Ying SUN
;
Wenli YU
- Keywords:
Liver transplantation;
Acute lung injury;
Child;
Troponin;
Biliary atresia
- From:
Chinese Journal of Organ Transplantation
2016;37(10):581-585
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the impact of cardiac troponin Ⅰ (cTnI) on acute lung injury in pediatric living donor liver transplant children with biliary atresia.Methods The clinical data of 112 pediatric living donor liver transplant recipients with biliary atresia in Tianjin First Central Hospital from February 2011 to September 2015 were retrospectively reviewed.Fifty-five recipients with cTnI ≥0.07 μg/L served as high-cTnI group and 57 recipients with cTnI group ＜0.07μg/L as normalcTnI group.The clinical data between two groups were compared and the association between serum cTnI level and acute lung injury after living-donor liver transplantation was evaluated by logistic regression analysis.Results The percentage of acute lung injury after pediatric living donor liver transplantation in high-cTnI group and normal-cTnI group was 31.6％ and 9.1％,respectively.Intratransplant cTnI ≥0.07μg/L (OR =4.489,confidence interval 1.170-17.226) was the risk factor for acute lung injury after transplantation.The value of cTnI showed the positive correlation with preoperative PELD scores (OR =4.489,confidence interval 1.170-17.226).Conclusions Intratransplant cTnI level was the significant prognostic risk factor in acute lung injury after pediatric living-donor liver transplantation for children with biliary atresia.The cTnI level was associated with preoperative PELD scores.
