Advances in Study on Effects of Helicobacter pylori Eradication Therapy on Intestinal Microecology
10.3969/j.issn.1008-7125.2017.04.011
- VernacularTitle:幽门螺杆菌根除治疗对肠道微生态影响的研究进展
- Author:
Jing LI
;
Le LIU
;
Ye CHEN
- Keywords:
Helicobacter pylori;
Eradication Therapy;
Intestinal Microecology;
Probiotics
- From:Chinese Journal of Gastroenterology
2017;22(4):241-244
- CountryChina
- Language:Chinese
-
Abstract:
It is documented that nearly half of the global population have been infected with Helicobacter pylori (Hp).In Chinese consensus report on management of Hp infection,bismuth quadruple therapy composed of proton pump inhibitor,bismuth and two antibiotics is recommended as the first-line Hp eradication regimen.However,large doses of oral antibiotics and PPI often disrupt the well-balanced host-microbial symbiotic state,and impair the protective effect of biological barrier.Furthermore,the alteration of microbial composition secondary to eradication therapy might be associated with the increased adverse effects of Hp eradication therapy and re-infection.This paper summarized the advances in study on effects of Hp eradication therapy on intestinal microecology and the advantages of probiotics supplementation in Hp eradication therapy.
