Advances in Study on Gut Microbial Ecosystem and Gastroesophageal Reflux Disease
10.3969/j.issn.1008-7125.2017.04.012
- VernacularTitle:胃肠道微生态系统与胃食管反流病关系的研究进展
- Author:
Xiaoxue SHEN
;
Ting YU
;
Lin LIN
- Keywords:
Microbial Consortia;
Gastrointestinal Tract;
Gastroesophageal Reflux Disease;
Inflammation;
Autonomic Nervous System;
Probiotics
- From:
Chinese Journal of Gastroenterology
2017;22(4):245-248
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal tract contains the most complicated microbial ecosystem of the human body,and balance of microbial ecosystem has been proved to play an important role in human health.Gastroesophageal reflux disease (GERD) is closely related to the esophageal,gastric and intestinal microecology.It has been revealed that alterations in gut microbial ecosystem may induce mucosal inflammation,relax lower esophageal sphincter (LES),increase intragastric pressure and delay gastric emptying via various pathways and subsequently cause or exacerbate gastroesophageal reflux.In this article,the advances in study on gut microbial ecosystem and GERD were reviewed.
