Efficacy and safety of Tanreqing injection in the treatment of elder chronic senile obstructive pulmonary disease
10.3969/j.issn.1005-1678.2017.04.036
- VernacularTitle:痰热清注射液治疗老年慢性阻塞性肺疾病的临床疗效及安全性
- Author:
Guijuan LI
;
Jie CAO
;
Guihong YANG
- Keywords:
Tanreqing injection;
chronic senile obstructive pulmonary disease;
efficacy;
safety
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):112-114
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of Tanreqing injection in the treatment of elder chronic senile obstructive pulmonary disease.Methods 78 cases of chronic senile obstructive pulmonary disease patients from August 2014 to May 2015 in our hospitol were selected and divided into control group and experiment group,with 39 cases in each group.The patients in the both groups were give regular treatment,patients in the control group were given theophylline sustained release tablets 0.2 g oral,two times a day;The experiment group were treated on base of the control group were given Tanreqing injection 20mL+5％intravenous glucose injection 500mL.The clinical efficacy,type B brain natriuretic peptide(BNP),calcitonin(PCT),forced vital capacity(FVC),forced expiratory volume in one second(FEV1),forced vital capacity(FVC)/expected value,and adverse reactions were compared between the two groups.Results The clinical efficacy in experiment group was 94.87％,which significant higher than that in control group(82.05％,P<0.05).The level of BNP serum PCT in two groups after treatment were significantly decreased,and the experiment group was significantly lower than the control group(P< 0.05);FEV1/expected,value FEV1/FVC levels were significantly increased and the experiment group was significantly higher than that of the control group(P< 0.05).The adverse drug reactions was not statistically different between the two groups.Conclusion Tanreqing injection in the treatment of elder chronic senile obstructive pulmonary disease with significant clinical efficacy,and with high safety.
