Effect of compound rhubarb gallnut gargle combined with periodontal basic therapy on inflammatory factors in chronic periodontitis
10.3969/j.issn.1005-1678.2017.04.049
- VernacularTitle:复方大黄五倍子含漱液联合牙周基础治疗对慢性牙周炎患者炎症因子水平的影响
- Author:
Lingling JIANG
;
Yan ZHAO
;
Senyang CHU
- Keywords:
periodontitis;
interleukin;
high sensitivity C-reactive protein;
compound rhubarb gallnut;
tumor necrosis factor-α
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):152-154
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the compound rhubarb gallnut gargle combined periodontal treatment effect on inflammatory factors in patients with chronic periodontitis.Methods 76 patients with chronic periodontitis from June 2014 to May 2015 in our hospital were selected and randomly divided into two groups,given periodontal treatment as control group,compound rhubarb gallnut gargle combined periodontal treatment as observation group,38 cases in each group,two groups were detected after treatment of gingival crevicular fluid levels of inflammation.Results After treatment,the gingival crevicular fluid of tumor necrosis factor-α(alpha TNF-α),high sensitive C-reactive protein(hs-CRP)and interleukin three(IL-6,IL-1 beta and IL-8)of two groups were significantly lower than those before treatment,and the observation group of inflammatory cytokine levels were significantly lower than the control group,the difference was statistically significant(P<0.05).The gingival index(GI)and gingival bleeding index(SBI)of the two groups were were lower than those before treatment,and the GI and SBI in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion In the treatment of chronic periodontitis,compound rhubarb gallnut gargle combined periodontal basic treatment effect,can significantly reduce the level of inflammation.
