Clinical efficacy of Liuweianxiao capsule combined with omeprazole to the treatment of functional dyspepsia
10.3969/j.issn.1005-1678.2017.04.052
- VernacularTitle:六味安消胶囊联合奥美拉唑治疗功能性消化不良的临床效果观察
- Author:
Tiesheng PAN
;
Jun ZHANG
;
Fengping TAN
- Keywords:
Liuweianxiao capsule;
omeprazole;
functional dyspepsia
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):161-163
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Liuweianxiao capsule combined with omeprazole to the treatment of functional dyspepsia.Methods 111 patients with functional dyspepsia from June 2014 to June 2016 were randomly divided into observation group 55 cases and control group 56 cases.The control group received Omeprazole treatment,observation group were given Liuweianxiao capsule combined with omeprazole.Recorded and analyzed motilin levels,EGG frequency changes,antral contraction amplitude,symptom score,the clinical efficacy and adverse reactions during treatment.Results ①After treatment,Motilin and EGG frequency levels were(491.59±25.01)mg/L、(2.92±0.34)cpm,better than the control group(416.73±23.14)mg/L、(1.89±0.23)cpm,and the differences were statistically significant(P<0.05).② After treatment,antral contraction amplitude levels were(1.60±0.09)％,better than the control group(1.34±0.07)％,and the differences were statistically significant(P<0.05).③After treatment,symptom score levels were(10.56±1.74)point,better than the control group(14.68±2.13)point,and the differences were statistically significant(P<0.05).④The total effective rate of observation group after treatment was 90.91％,significantly higher than the control group 73.21％,and the differences were statistically significant(P<0.05).⑤ The adverse reactions of observation group during treatment was 7.27％,and compared to the control group 10.71％,the difference was not significant.Conclusion Liuweianxiao capsule combined with Omeprazole can effectively remission related symptoms,and it is a safe and effective treatment.
