Comparison of efficacy and adverse reactions of oxaliplatin combined with gemcitabine and S-1 combined with cisplatin for advanced three negative breast cancer
10.3969/j.issn.1005-1678.2017.04.097
- VernacularTitle:应用奥沙利铂联合替吉奥以及吉西他滨联合顺铂方案对晚期三阴性乳腺癌的疗效与不良反应比较
- Author:
Yun BAI
;
Yang TAO
;
Chongjie WANG
;
Wenshu ZUO
- Keywords:
oxaliplatin;
tegafur gimeracil oteracil potassium capsule;
gemcitabine;
cisplatin;
triple negative breast cancer
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):293-295
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and adverse reactions of SOX and GP combined with two chemotherapy methods.Methods From January 2014 to September 2016 came to our hospital for treatment of three advanced breast cancer patients with negative 84 cases as the research object of observation,were randomly divided into SOX group and GP group were given chemotherapy measures and clinical observation on the treatment of.Results Two groups of patients with CR,PR,SD,PD,the number of cases and the total effective rate comparison,P values were 0.693,0.637,0649,0.801,0.823; two groups of patients with diarrhea,liver damage,thrombocytopenia,nausea and vomiting,neurotoxicity,anemia,leukopenia,rash,renal toxicity,appetite the incidence rate of decline,P values were 0.374,0.629,0.643,0.374,0.645,0.434,0.450,0.693,0.645,0.815.Conclusion Standard chemotherapy regimens for advanced three negative breast cancer was not uniform,but the SOX and GP regimens are safe and effective,can be used for clinical treatment.
