Role of Collagen Metabolism in Liver Fibrosis and Research Progress in Traditional Chinese Medicine on the Regulation of Collagen Metabolism
- VernacularTitle:胶原代谢在肝纤维化中的作用及中药调控胶原代谢研究进展
- Author:
Fansheng QU
;
Yu CHENG
;
Jinyong PENG
;
Lina XU
- Keywords:
Hepatic fibrosis;
Collagen metabolism;
Traditional Chinese medicine;
Anti-hepatic fibrosis effect
- From:
China Pharmacist
2017;20(4):728-731
- CountryChina
- Language:Chinese
-
Abstract:
The abnormal accumulation of extracellular matrix (ECM) in liver is the main feature of hepatic fibrosis,and collagen is the most important component in ECM.Collagen plays an important role in the occurrence and development of liver fibrosis.Therefore,to find traditional Chinese medicine with significant effect on collagen metabolism has become a critical approach for the treatment of hepatic fibrosis.This review summarized the role of collagen metabolism in liver fibrosis,and the research progress in traditional Chinese medicines with anti-hepatic fibrosis effect by regulating collagen metabolism was explored as well.
