Clinical curative effect and safety of application of Jiegu pill in the conservative treatment of patients with middle clavicle fracture
10.3969/j.issn.1005-1678.2017.04.057
- VernacularTitle:接骨丸在锁骨中段骨折保守治疗中应用的临床疗效及安全性
- Author:
Huanze JIANG
;
Fuhua ZHONG
- Keywords:
jiegu pill;
middle clavicle fracture;
conservative treatment;
clinical efficacy;
safety
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):175-176
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical curative effect and safety of application of Jiegu pill in the conservative treatment of patients with middle clavicle fracture.Methods Fifty-four cases of patients with middle clavicle fracture were randomly divided into the control group and treatment group,27 cases in each group.Two groups of patients were treated with conservative treatment,the control group was given Jiegu Qili Pian1.5g,bid,oral; the experimental group was treated with Jiegu pill 3.0g,bid,oral.Before and after treatment,compared between the two groups of patients with serum Osteocalcin(BGP),total type I collagen amino terminal peptide(TPINP),alkaline phosphatase(ALP)levels,efficiency of treatment and incidence of adverse reactions.Results After treatment,compared with the control group,the serum levels of BGP、TPINP and ALP were higher in the experimental group(P<0.05).The treatment efficiency of the experimental group(96.29％)was significantly higher than that of the control group(77.78％)(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion The Jiegu pill can significantly improve the serum levels of BGP、TPINP and ALP in patients with middle clavicle fracture,promote fracture healing,the clinical efficacy and safety were high.
