Treatment of interstitial tubal pregnancy with Guizhi Fuling pill assisted with methotrexate and mifepristone
10.3969/j.issn.1005-1678.2017.04.058
- VernacularTitle:桂枝茯苓丸辅助氨甲蝶呤及米非司酮治疗输卵管间质部妊娠的临床观察
- Author:
Minhui GUO
;
Xiaoli LAI
;
Dan WANG
- Keywords:
Guizhi Fuling pill;
methotrexate;
mifepristone;
tubal interstitial pregnancy
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):177-179
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze treatment of tubal interstitial pregnancy with Guizhi Fuling pill assisted with methotrexate and mifepristone.Methods 90 cases tubal interstitial pregnancy patients from January 2015 to June 2016 were grouped by admission order and each group with 45 cases.Methotrexate and mifepristone therapy were given the control group,Guizhi Fuling pill assisted with methotrexate and mifepristone were given the observation group.Treatment success rate,β-HCG negative time,mass disappearance time,length of hospitalization and adverse reactions were compared.Results (After treatment,treatment success rate of observation group was 91.11％and 80.49％of tubal smooth,witch all higher than control group with(88.89％,77.50％),but the difference was not statistically significant.(For the treatment of two groups of patients with success,β-HCG negative time,mass disappearance time and length of hospitalization of observation group were(13.05±1.08,24.09±1.43,15.37±0.82)days,shorter than control group with(17.39±1.50,27.43±2.19,18.85±1.)days(P<0.05).③ During treatment,adverse reactions of observation group was 11.11％,lower than control group with 26.67％(P<0.05).Conclusion Guizhi Fuling pill assisted with methotrexate and mifepristone can shorten treatment time and reduce side effects for tubal interstitial pregnancy patients.
