The effect and safety of two kinds of antimicrobial agents in the treatment of children with bacterial enteritis
10.3969/j.issn.1005-1678.2017.04.110
- VernacularTitle:两种抗菌药物治疗小儿细菌性肠炎的效果及安全性分析
- Author:
Jie ZHANG
;
Yun WANG
- Keywords:
enteritis;
lamivudine;
safety
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):333-335
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of the application of the clinical effect of the use of lamivudine and the safety in the treatment of infantile enteritis.Methods From August 2013 to May 2016 in our hospital for diagnosis and treatment of 112 cases of enteritis were retrospectively analyzed,according to the application in the treatment of antibiotics into ceftazidime group in 60 cases,cefotiam group 52 cases,two groups of children with rehydration,correct electrolyte disorders such as basic treatment,the difference of clinical effect comparison.Results After 3d treatment,ceftazidime group stool frequency was significantly lower than that of cefotiam group(P<0.05); ceftazidime group the duration of diarrhea,stool leukocyte recovery time were significantly lower than cefotiam group(P<0.05); three day,five day after treatment of serum CRP,PCT levels were ceftazidime group significantly lower than cefotiam group(P<0.05); the two groups of serum CRP and PCT levels before treatment were significantly decreased(P<0.05); After five days treatment,5D after treatment,ceftazidime group the effective rate of 58.33％,effective 41.67％,invalid rate 0％,cefotiam group the effective rate was 42.31％,effective 53.85％,invalid rate 3.85％,ceftazidime treatment group is better than that of cefotiam group(P<0.05).Conclusion In the treatment of infantile enteritis,the effect is reliable and the safety is high.
