Efficacy and safety of levonorgestrel combined with danazol capsules in the treatment of endometriosis patients
10.3969/j.issn.1005-1678.2017.04.122
- VernacularTitle:左炔诺孕酮联合达那唑胶囊治疗子宫内膜异位症患者的疗效与安全性
- Author:
Qing WANG
;
Jianmiao HU
;
Heqing JIA
- Keywords:
levonorgestrel;
endometriosis;
safety;
ovarian function
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):370-372
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of levonorgestrel combined with danazol capsules in the treatment of endometriosis patients.Methods Ninety patients with endometriosis were randomLy divided into experimental group and control group(45 cases).The control group was treated with danazol capsules.The experimental group was treated with levonorgestrel on the basis of the control group.The clinical efficacy and serum CA125,CA199,ovarian function,and ovarian function were observed before and one month and three months after treatment.Adverse reaction rate.Results After three months of treatment,the clinical symptoms of the experimental group were lower than the control group(P<0.05); serum CA125,CA199 levels decreased,compared with the control group,the test group decreased significantly(P<0.05); ovarian function recovery Compared with the control group,the difference was statistically significant(P<0.05).two group compared with the incidence of adverse reactions,the difference was not statistically significant.Conclusion Levonorgestrel danazol capsules treatment of endometriosis Bitter patients than the use of danazol capsules better treatment,higher safety,worthy of clinical application to promote.
