Adverse reactions of lansoprazole combined with Flupentixol and melitracen in the treatment of functional dyspepsia patients
10.3969/j.issn.1005-1678.2017.04.129
- VernacularTitle:兰索拉唑联合氟哌噻吨美利曲辛治疗功能性消化不良患者的疗效及不良反应
- Author:
Hua ZHU
;
Shuangyang WANG
;
Yuanyuan HUA
- Keywords:
lansoprazole;
deanxit;
functional dyspepsia;
curative effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(4):391-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the curative effect and adverse reaction of lansoprazole combined with droperidol thiadiazole melitracen treatment in patients with functional dyspepsia.Methods From December 2013 to December 2015 in our hospital and accepted treatment of 90 patients with functional digestive adverse as the research object,according to the random number table were divided into the control group and the observation group,45 cases in each group.The control group by oral administration of lansoprazole enteric coated capsules,the observation group taking oral lansoprazole and droperidol thiadiazole melitracen,course lasted for 4 weeks,efficacy and adverse occurrence was compared between two groups of patients.Results After 4 weeks of treatment,the observation group with symptoms score GSRS(postprandial fullness discomfort,early satiety,abdominal pain,epigastric burning sensation were lower than the control group with postprandial fullness discomfort early satiety,abdominal pain,epigastric burning sensation,and the difference was statistically significant(P<0.05); the patients in the observation group after 4 weeks of treatment,the total effective rate(86.7％)was higher than the control group(66.7％)significantly,and difference was statistically significant(P<0.05); symptoms of adverse reactions of two groups of patients in the process of drug use were mild and did not give special treatment,in a few days after the basic relief.Conclusion Lansoprazole combined with fluorine Pai Sai tons of Murray Song Xin can effectively eliminate or reduce the symptoms of functional dyspepsia patients clinical and no serious adverse reactions,it is safe in clinical application.
