Advance in the development of modified vaccinia virus Ankara (MVA)vectors for novel influenza vaccines
10.3969/j.issn.1002-2694.2017.03.006
- VernacularTitle:基于改良型痘苗病毒安卡拉株载体的新型流感疫苗研究进展
- Author:
Yuan YIN
;
Weiling WANG
- Keywords:
influenza virus;
modified vaccinia virus Ankara;
viral vector vaccine
- From:
Chinese Journal of Zoonoses
2017;33(3):222-227
- CountryChina
- Language:Chinese
-
Abstract:
Influenza,caused by influenza virus,is a respiratory infectious disease with a serious hazard to human health.Prevention of influenza through vaccine development is the most effective strategy.It is important to build a rapid response platform for research and production of influenza vaccine.As virus vectors,live vaccine provides a new prevention and treatment way for infectious disease.Modified vaccinia virus Ankara(MVA) is a replication-deficient viral vector that is safe and can encode one or more foreign antigens and induce humoral and cellular immune response.MVA holds great promise as a vaccine platform.In this review,we discuss the use of MVA for vaccine development against influenza virus.
