Fecal bacteria transplantation for treatment of severe gastrointestinal disease caused by food allergy in children: a case report and literature review
10.3969/j.issn.1000-3606.2017.04.002
- VernacularTitle:粪菌移植治疗幼儿严重食物过敏性胃肠病1例并文献复习
- Author:
Zhongsheng ZHU
;
Yuejie ZHENG
;
Huabo CAI
;
Daming BAI
;
Dongling DAI
;
Jianli ZHOU
;
Shaoming ZHOU
- Keywords:
gastrointestinal disease caused by food allergy;
fecal transplantation;
treatment;
child
- From:
Journal of Clinical Pediatrics
2017;35(4):247-252
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore fecal bacteria transplantation for the treatment of severe gastrointestinal disease caused by food allergy. Method The therapeutic process of fecal bacteria transplantation for treatment of severe food allergy gastrointestinal disease was retrospectively analyzed, and the related literature was reviewed. Results A 2-year-old boy had onset of intestinal infection and diarrhea was persistent even though he had received adequate anti-infection therapy and supportive treatment. Finally, the patient received the treatment of fecal bacteria transplantation and the symptoms were then improved. No adverse reactions were observed in 2 months of follow-up. In foreign literature, fecal bacteria transplantation in children is mainly applied to clostridium difficile infection (CDI) and inflammatory bowel disease (IBD), with efficiency of 90%- 100% and 55.6% - 100%, respectively. While in the domestic literature, fecal bacteria transplantation in children is mainly used in CDI and antibiotic associated diarrhea, and the effective rate is 100%. No serious adverse reactions were found in all the researches. Conclusion Fecal transplantation is safe and effective in the treatment of children with severe gastrointestinal disease caused by food allergy, but its application in children is not yet mature and needs more in-depth researches.
