Clinical features and treatment of thyroid carcinoma in children
10.3969/j.issn.1000-3606.2017.04.010
- VernacularTitle:儿童甲状腺癌的临床特点及治疗分析
- Author:
Xiaomin WANG
;
Shiyin MA
;
Yuefeng HAN
;
Mingjie ZHANG
;
Hui LI
;
Deshang CHEN
;
Jun QIAN
;
Xinquan TAO
- Keywords:
thyroid carcinoma;
treatment;
child
- From:
Journal of Clinical Pediatrics
2017;35(4):282-285
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features and treatment of thyroid carcinoma in children. Method The clinical data of 19 children under 14 years old with thyroid carcinoma diagnosed and treated from January 2003 to January 2014 were retrospectively analyzed. Results In 19 cases (12 males and 7 females), there were 18 cases of papillocarcinoma and one case pf follicular carcinoma. Unilateral lobectomy plus isthmectomy was performed in 6 cases, subtotal thyroidectomy in 4 cases and total thyroidectomy in 9 cases. Unilateral cervical lymph node dissection was performed in 5 cases and bilateral in 11 cases. After the operation, multiple lesions were confirmed by pathology in 9 cases, thyroid capsular invasion in 14 cases, lymphatic metastasis in 15 cases and distant metastasis in 5 cases. All the patients were treated with TSH, and 10 cases were treated with 131I after operation. The median follow-up time was 63 months. There was no death in all cases, while local residual tumor recurrence was found in 2 cases and cervical lymph node metastasis in 2 cases and distant metastasis in one case. Conclusion Thyroid carcinoma in children is mostly well-differentiated, so the overall prognosis is better. However, children who have extracapsular invasion, multiple lesions in bilateral thyroid, cervical lymph node metastasis and distant metastasis are at high risks and should be treated with comprehensive therapy that includes total thyroidectomy.
