Surveillance of antibiotic resistance in the clinical isolates collected from Shanghai Xinhua Hospital Chongming Branch during 2015
10.16718/j.1009-7708.2017.02.008
- VernacularTitle:上海新华医院崇明分院2015年临床常见细菌耐药性监测
- Author:
Minjian QIAN
;
Baoshan WAN
;
Li ZHANG
;
Xiaocui WU
;
Jin CHEN
- Keywords:
bacterial identification;
antimicrobial resistance surveillance;
carbapenem-resistant Enterobacteriaceae;
vancomycin-resistant Enterococcus
- From:
Chinese Journal of Infection and Chemotherapy
2017;17(2):159-166
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the antimicrobial resistance profile of clinical isolates in Shanghai Xinhua Hospital Chongming Branch affiliated to Shanghai Jiaotong University School of Medicine , a member of China Antimicrobial Resistance Surveillance System, during 2015, for the purpose to facilitate rational antimicrobial therapy. Methods Strain identification?and?susceptibility?testing?were?carried?out?for?the?clinical?isolates?using?MicroScan?WalkAway?96?Automated?Systems and Kirby-Bauer method. Results In 2015, a total of 1815 isolates were collected, including gram-negative bacteria (73.2 %) and gram-positive bacteria (26.8 %). The top three frequently isolated species were Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. ESBL-producing strains were found in 36.3 % of the Escherichia coli isolates, 12.6 % of the Klebsiella (K. pneumoniae and K. oxytoca) isolates, and 28.0 % of the Proteus mirabilis isolates. The prevalence of carbapenem-resistant strains was 0.69 % in Enterobacteriaceae isolates. The prevalence of methicillin-resistant strain was 29.1 % in S. aureus, and 61.4 % in coagulase-negative Staphylococcus isolates. No more than 15 % of the Enterobacteriaceae isolates and no more than 20 % of the P. aeruginosa and Acinetobacter isolates were resistant to carbapenems. No vancomycin-or linezolid-resistant strains were found in Enterococcus or Staphylococcus. Conclusions Antibiotic-resistant clinical isolates are a serious threat for clinical antimicrobial treatment. We should pay more attention to such urgent situation and rational use of antibiotics.
