Performance of parallel test in detecting malaria infection for returnees from malaria endemic area
10.3969/j.issn.1673-4130.2017.01.003
- VernacularTitle:平行诊断试验监测疟疾流行区归国人员疟原虫感染者的性能评价
- Author:
Lan WEN
;
Bin TIAN
;
Xiaojun SHEN
;
Yu LIAO
;
Bing ZHANG
- Keywords:
plasmodium;
thick blood smear;
rapid diagnostic test;
performance;
parallel test
- From:
International Journal of Laboratory Medicine
2017;38(1):7-9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the performance of parallel test in detecting malaria infection for returned person from malaria endemic area.Methods The blood samples of 484 returnees from malaria endemic area were analyzed and detected by thick blood smear,rapid diagnostic test (RDT) and nest PCR in four companies involving the African labor dispatching.Results The sensitivi ty of thick blood smear and RDT was 0.628 and 0.744 respectively,which of the parallel test was 0.930.On the other hand,the area under the curve (AUC) of parallel test was 0.930 (95％CI:0.895-0.986),which was higher than thick blood smear[0.814 (95％CI:0.724-0.904)]and RDT[0.847 (95％CI:0.769-0.926)].Conclusion Thick blood smear and RDT,which consist of parallel test,could improve the detection sensitivity and accuracy for returnees from malaria epidemical area effectively.This approach is worthy of popularization and application.
