Species Specificity of Male Human's 29 Y-SNP Loci
- VernacularTitle:人类男性29个Y-SNP位点种属特异性
- Author:
Zengjie HUANG
;
Huifang CHEN
;
Guohua FENG
;
Lanjiang LI
;
Bingying XU
- Keywords:
Species specificity;
Y-SNP;
Forensic science;
Forensic application
- From:
Journal of Kunming Medical University
2016;37(9):40-44
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore species specificity of 29 Y-SNP loci and to lay the foundation for forensic application.Methods Human DNA and 8 different kinds of common animals' DNA were amplified separately by PCR.The PCR products were analyzed with PAGE.Results Twenty-three out of 29 Y-SNP loci were only amplified by the male human DNA,which indicated a good species specificity.Three loci amplified from human and some animals showed that the length of the product was different between two species.Another three loci amplified from human and animal showed that the length of the fragment was similar between human and animal.Five loci were amplified by PCR products from both male and female samples.Conclusion Most of 29 Y-SNP loci,amplified in male humans,have good species specificity and can be directly used for personal identification and paternity testing.
