Research progress in genetic susceptibility to alcoholic liver disease
10.3969/j.issn.1001-5256.2017.02.039
- VernacularTitle:酒精性肝病的遗传易感性研究现状
- Author:
Funing YANG
;
Jing HUANG
- Keywords:
liver diseases,alcoholic;
genetic predisposition to disease;
polymorphism,single nucleotide;
review
- From:Journal of Clinical Hepatology
2017;33(2):379-383
- CountryChina
- Language:Chinese
-
Abstract:
Alcoholic liver disease (ALD) is one of the most common chronic liver diseases in clinical practice with a complicated pathogenesis.Genetic factors play an important role in the pathogenesis of ALD and might be the potential targets for the treatment of ALD.This article reviews the susceptibility genes associated with ALD in recent years and points out that the exploration of the mechanisms of action of these genes in the development and progression of ALD can provide a theoretical basis for effective evaluation,diagnosis,and prevention and treatment of ALD in clinical practice.
