Significance of Hcy ,folic acid ,PLT ,MPV and PDW detection in patients with recurrent spontaneous abortion
10.3969/j.issn.1673-4130.2017.05.015
- VernacularTitle:Hcy、叶酸、PLT、MPV、PDW检测对反复性流产患者的意义
- Author:
Qian LI
;
Chunyan MA
- Keywords:
homocysteine;
folic acid;
platelet;
recurrent spontaneous abortion
- From:
International Journal of Laboratory Medicine
2017;38(5):613-614
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the platelet function in the patients with recurrent spontaneous abortion (RSA) ,to explore the correlations between Hcy and folic acid(FA)with mean platelet volume(MPV) and platelet distribution width(PDW) ,and to evalu-ate the application value of above indicators in predicting RSA .Methods Twenty-eight cases of RSA ,40 cases of healthy pregnancy and 50 healthy child-bearing women(control group) in our hospital were selected .The detection indicators included peripheral blood Hcy ,FA ,PLT ,MPV and PDW .Results The PLT and FA levels in the patients group were significantly lower compared with the normal pregnancy group and control group(P<0 .01) ,while the Hcy ,PDW and MPV were increased(P<0 .05);the various indica-tors had no statistically significant difference between the normal pregnancy group and control group (P>0 .05) .Blood Hcy was negatively correlated with PLT and FA ;Hcy and FA were negatively correlated in the normal pregnancy group ,other indicators had no obvious correlation(P>0 .05) .Conclusion The Hcy metabolism abnormality ,platelet parameter changes and their interactions may be related to RSA .The combined detection of Hcy ,FA and platelet parameters has a certain clinical significance to early diag-nosis and treatment of RSA .
