Clinical Observation of Runchang Xuanfei Shugan Formula in Treatment of Slow Transit Constipation
10.3969/j.issn.1005-5304.2017.05.007
- VernacularTitle:润肠宣肺疏肝方治疗慢传输型便秘临床观察
- Author:
Tao LIU
;
Xia ZHANG
;
Wei WEI
- Keywords:
slow transit constipation;
Runchang Xuanfei Shugan formula;
clinical efficacy
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2017;24(5):27-30
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Runchang Xuanfei Shugan Formula in the treatment of slow transit constipation. Methods Totally 94 patients were randomly divided into treatment group and control group, with 47 patients in each group. Treatment group was given Runchang Xuanfei Shugan Formula, one dose per day, half a dose for morning and half a dose for evening, and the control group was given lactulose oral liquid, 15 mL each time, for morning and evening, and citrate moser Billy 5 mg, three times a day orally taken before meals. The treatment course for the two groups were 4 weeks, with three-month follow-up. The defecation symptom score, anxiety and depression score were observed, the colonic transit test meter was performed, and the side effects were recorded. Results The degree of defecation difficulty, defecation frequency, defecation time, abdominal distension and stool quality score of the two groups significantly decreased after treatment (P<0.05), and the treatment group was much lower than the control group after treatment and three months after treatment (P<0.05). The score of anxiety and depression (SAS, SDS) of the treatment group decreased significantly after treatment and three months after treatment (P<0.05), and had significant differences with the control group (P<0.05). The colon function was significantly improved after treatment in both groups (P<0.05), without statistical significance (P>0.05). Conclusion Runchang Xuanfei Shugan Formula can improve clinical symptoms of slow transit constipation, ease anxiety and depression of patients, and promote colon transmission function.
