Function of purinergic receptorsin communication between neurons and glial cells
10.3969/j.issn.1001-1978.2017.04.002
- VernacularTitle:嘌呤受体在神经元和神经胶质细胞间信息传递中的作用
- Author:
Xuan SHENG
;
Guilin LI
- Keywords:
purinergic receptors;
purine nucleotides;
neuron;
glial cell;
communication;
neurological diseases
- From:
Chinese Pharmacological Bulletin
2017;33(4):450-454
- CountryChina
- Language:Chinese
-
Abstract:
The function of the nervous system is largely determined by the communication between neurons and glial cells.The interaction of complex signaling pathways between neurons and glial cells involves in a variety of signaling molecules.Purines and the purinergic receptors play a crucial role in the process of the interaction.For a long time, the study on the central nervous system is mainly focused on neurons, while glial cells are mainly used as support cells or in response to brain injury to provide a guiding role.The latest research shows that glial cells play an important role in the occurrence and development of nervous system diseases.We will summarize the function of purinergic receptors in the interaction of neurons and glial cells and in neurological diseases.
