An Association Analysis of Different Types of Dyslipidemia and Heart Rate Variability in Patients with Type 2 Diabetes
10.11969/j.issn.1673-548X.2017.03.029
- VernacularTitle:2型糖尿病患者血脂紊乱类型与心率变异性相关性分析
- Author:
Zhepu YANG
;
Huimin BI
- Keywords:
Type 2 diabetes;
Dyslipidemia;
Heart rate variability
- From:
Journal of Medical Research
2017;46(3):115-119
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of different types of dyslipidemia on heart rate variability in patients with type 2 diabetes.Methods Cohort study was carried out at Renmin Hospital of Wuhan University during January 2014 to May 2016.Total 725 patients with type 2 diabetes were recruited,including 231 patients without dyslipidemia and 494 patients with dyslipidemia.Clinical parameters were collected from electronic medical records system.Using variance analysis,chi square test,Pearson correlation analysis and partial correlation analysis,we explored an association of different types of dyslipidemia and heart rate variability in patients with type 2 diabetes.Results TG,LDL-C,HDL-C,TG + HDL-C group significantly decreased heart rate variability compared group without dyslipidemia (P < 0.05).But the partial correlation analysis showed that only atherogenic index of plasma and Triglyceride (TG) were negatively correlated with heart rate variability,HDL cholesterol was positively correlated with heart rate variability,and the difference was statistically significant (P < 0.05).Conclusion Triglyceride (TG),atherogenic index of plasma(AIP),HDL cholesterol were related to the reduction heart rate variability in patents with type 2 diabetes.