Application of cyclosporine A in noninfectious uveitis
10.13389/j.cnki.rao.2017.0074
- VernacularTitle:环孢素A在非感染性葡萄膜炎治疗中的应用
- Author:
Nan ZHANG
;
Hong LU
- Keywords:
noninfectious uveitis;
cyclosporine A;
immunosuppressant;
combined therapy
- From:
Recent Advances in Ophthalmology
2017;37(3):293-297
- CountryChina
- Language:Chinese
-
Abstract:
Uveitis is a kind of refractory blinding eye diseases.Noninfectious uveitis is an important part of uveitis,which is thought to be an autoimmune disease,and systemic immunosuppressive therapy is usually required to prevent visual loss.As a selective T-cell inhibitor,cyclosporine A is one of the most widely used immunosuppressants,and has obvious therapeutic effect on many kinds of uveitis.Cyclosporine A combined with glucocorticoid,other immunosuppressants or biological agents can improve the therapeutic effect and reduce the side effects.Recently,the inhibitory effect on glucocorticoid-resistant Th17 cells and topical application of cyclosporine A,show its advantage and potential in the treatment of noninfectious uveitis.
