A clinical analysis on fever of unknown origin in in-patients with systemic lupus erythematosus

VernacularTitle:系统性红斑狼疮合并不明原因发热的病因分析
Author: Caifeng ZHANG ; Rui XU ; Mengtao LI ; Xiaofeng ZENG
Keywords: Lupus erythematosus,systemic; Fever of unknown origin
From: Chinese Journal of Internal Medicine 2017;56(4):295-297
CountryChina
Language:Chinese
Abstract: To investigate the etiology and differential diagnoses of patients with systemic lupus erythematosus (SLE) and fever of unknown origin (FUO).From January 2012 to December 2014,a total of 928 SLE patients were admitted to Peking Union Medical College Hospital.Only 50 patients were combined with FUO (5.4％).The most common reason of fever was caused by infections (33 cases,66.0％),including bacterial infection in 17 cases with 5 tuberculosis,viral infection in 11 cases,and fungal infection in 5 cases.The second reason offever was due to poor disease control or recurrence in 17 patients (34.0％).No fever was caused by malignant tumor.When clinical data was compared between 17 non-infected patients versus 33 infected patients,C reactive protein and procalcitonin in the infected group were significantly higher than those in the non-infected group.In SLE patients combined with FUO,infection is the most common etiology which is necessary to be paid attention to.