Comparison of gene frequencies of short tandem repeats loci on Y Chromosome between offenders with initiative-aggressive behavior and impulsive-aggressive behavior
10.3760/cma.j.issn.1674?6554.2017.03.009
- VernacularTitle:Y染色体短串联重复序列基因座基因频率在主动与冲动攻击行为群体中分布的比较
- Author:
Shuyou ZHANG
;
Huajie BA
;
Chun YANG
;
Yin WANG
;
Hanqing ZHAO
;
Zhiqin GAO
- Keywords:
Initiative?aggressive behavior;
Impulsive?aggressive;
Human Y chromosome;
Short tandem repeats( STRs);
Genetic polymorphism
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2017;26(3):237-241
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the distributional differences of the gene frequencies of 22 short tandem repeats loci on Y Chromosome(Y?STRs) between offenders with Initiative?aggressive behavior and impulsive?aggressive behavior,and to probe into the genetic factors of initiative?aggressive behavior and im?pulsive?aggressive behavior. Methods Biological samples of 271 offenders with initiative?aggressive behav?ior and 271 offenders with impulsive?aggressive behavior were collected and PCR compound amplification was carried out with the aid of PowerPlex Y23 System. Then the PCR products were subjected to electrophoresis and gene detection with AB3500xL gene analysis system so as to calculate and compare the alleles and haplo?types of 22 Y?STRs gene frequency in the two groups. Results The distribution of allele frequency were sig?nificantly difference in locus DYS437(P=0.022) between two groups,not in the other 21 Y?STRs loci( all P>0.05) . Univarite analysis showed significant differences at allelle 14 in locus DYS437 between both groups ( initiative?aggressive behavior group:69. 37%;impulsive?aggressive behavior group:58. 67%; P=0. 009 ) . Conclusion Loci DYS437 may be associated with aggressive behavior. In the group of aggressive behavior, allelle 14 on locus DYS437 may be the susceptible factor of initiative?aggressive behavior and the resistant factor of impulsive?aggressive.
