Research progress in chemical constituents, anti-inflammatory effect and mechanism of Folium Perillae
10.3867/j.issn.1000-3002.2017.03.012
- VernacularTitle:紫苏叶化学成分、抗炎作用及其作用机制研究进展
- Author:
Hui YANG
;
Pei MA
;
Mingbao LIN
;
Qi HOU
- Keywords:
Folium Perillae;
chemical constituents;
inflammation
- From:
Chinese Journal of Pharmacology and Toxicology
2017;31(3):279-286
- CountryChina
- Language:Chinese
-
Abstract:
Folium Perillae (FP) is a traditional Chinese materia medica, which has been used for treating inflammatory diseases. In order to clarify the material basis of FP' s pharmacological activity and anti-inflammatory mechanism, we presented a review about some of the primary chemical components in FP, such as volatile oils, flavonoids, anthocyanins, phenolic acids, glycosides, triterpenes and steroids, and about the anti-inflammatory activity of FP extract and its major mechanism, such as regulating the viability and function of innate immune cells, controlling the balance of helper T cells, based on related research in recent years. This study aims to provide reference for further research and development of new drugs based on FP.
