Value of TNR and TLR of 18F-FDG PET/CT Tumor Metabolic Imaging in Diagnosis of Lung Cancer
10.3969/j.issn.1005-5185.2016.12.015
- VernacularTitle:肿瘤/对侧肌肉比值与肿瘤/肝脏比值在18F-FDG PET/CT肿瘤代谢显像诊断肺癌中的价值
- Author:
Ying WANG
;
Pengfei YANG
;
Yanmei LI
;
Juan LI
;
Feng ZHAO
- Keywords:
Lung diseases;
Lung neoplasms;
Positron-emission tomography;
Tomography,X-ray computed;
Fluorodeoxyglucose F18;
Diagnosis,differential
- From:
Chinese Journal of Medical Imaging
2016;24(12):934-936
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate the role of 18F-FDG PET/CT tumor metabolic imaging in the detection of lung cancer lesions,using receiver operating characteristic (ROC) curves analysis and investigate the diagnostic value of TNR and TLR in lung lesions.Materials and Methods A total of 82 patients who were confirmed with lung space-occupying lesionsby 18F-FDG PET/CT tumor metabolic imaging were retrospectively analyzed.Based on the pathological gold standard,evaluate the diagnostic value of 18F-FDG PET/CT tumor metabolic imaging in lung space-occupying lesions by t-test and ROC curve.Results There was a significant difference of TNR and TLR between benign and malignant lesion (P＜0.01).The AUC on ROC curve of TLR ratio was 0.943 in the lung lesions while the TNR was 0.927.The sensitivity,specificity and the accuracy were 86.36％,62.50％ and 81.71％,respectively with the TNR cutoff of 6.87.The sensitivity,specificity and the accuracy were 90.91％,68.75％ and 86.58％,respectively with the TLR cutoff of 2.86.Conclusion 18F-FDG PET/CT tumor metabolic imaging is useful for differentiating lung space-occupying lesions.But for cases of atypical 18F-FDG uptake,it is suggested to combine with clinical information.
