An update on diagnosis and treatment of invasive aspergillosis in children
10.3760/cma.j.issn.2095-428X.2017.06.004
- VernacularTitle:儿童侵袭性曲霉病诊治进展
- Author:
Ying WANG
- Keywords:
Invasive aspergillosis;
Diagnosis;
Treatment;
Immunocompromised;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(6):412-416
- CountryChina
- Language:Chinese
-
Abstract:
Invasive aspergillosis (IA) is a major cause of morbidity and mortality in immunocompromised children.The purpose of the review was to provide epidemiological,clinical aspects,diagnosis and antifungal treatment options in the pediatric population.Diagnosis of IA remains a challenge as the clinical and imaging manifestations are not specific,and a histological diagnosis is often unfeasible,and blood culture shows low sensitivity rates.In recent years,great progress has been made in the detection of fungal biomarkers,which is mainly described in this paper.