Therapeutic Effects of Magnesium Sulfate Combined with Budesonide and Terbutaline Sulfate Inhalation for the Treatment of Bronchiolitis
- VernacularTitle:硫酸镁联合布地奈德、硫酸特布他林雾化吸入治疗毛细支气管炎疗效
- Author:
Youbiao SONG
;
Xinya ZHANG
- Keywords:
Bronchiolitis;
Magnesium sulfate;
Budesonide;
Terbutaline sulfate;
Inhalation therapy
- From:
Journal of Kunming Medical University
2016;37(9):71-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of magnesium sulfate inhalation combined with budesonide and terbutaline sulfate nebulizer for the treatment of bronchiolitis.Methods Sixty children with bronchiolitis were randomly divided into observation group and control group with 30 cases in each group.Children in the control group received routine treatment and the observation group were inhaled with magnesium sulfate combining budesonide and terbutaline sulfate.Curative effects were evaluated in the aspects of the clinical symptoms,serum inflammatory factors and overall clinical efficacy.Results The symptoms in children including asthma,shortness of breath,coughing,wheezing and lung auscultation were significantly alleviated within a shorter period of time than that in the control group (P＜0.05).The serum levels of TNF-u,IL-6,IL-8 and TIgE were significantly reduced in both groups after the treatment (P＜0.05).But in the observation group,the alleviation of the symptoms was significantly greater than that in the control group (P＜0.05).The overall effective rate in the observation group and the control group was 93.3％ and 70.0％ respectively (P＜0.001).Conclusion The clinical efficacy of inhaling magnesium sulfate with budesonide and terbutaline sulfate to treat bronchiolitis is satisfactory and worth clinical application.
