Treatment of Acne.
10.5124/jkma.2006.49.1.63
- Author:
Kyu Uang WHANG
1
Author Information
1. Department of Dermatology, Soonchunhyang University College of Medicine and Hospital, Korea. snolomas@hosp.sch.ac.kr
- Publication Type:Original Article
- Keywords:
Acne;
Pilosebaceous Unit;
Comedone;
Retinoid
- MeSH:
Acne Vulgaris*;
Adolescent;
Humans;
Sebaceous Glands
- From:Journal of the Korean Medical Association
2006;49(1):63-69
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acne vulgaris is a self-limited disease, seen primarily in adolescents. Most cases of acne are pleomorphic, presenting various lesions consisting of comedones, pustules, and nodules. Although it has been traditionally classified as a disease of the sebaceous gland, it actually involves the pilosebaceous unit. There are four major principles in the treatment of acne: (1) correct the altered pattern of follicular keratinization; (2) decrease the sebaceous gland activity; (3) decrease the follicular bacterial population; and (4) produce anti-inflammatory effect. The natural course of acne varies greatly, and therefore, the determination of the therapeutic efficacy of medications for the treatment of acne is far from being simple.
