Expression of heat shock protein 70 in periodontium during orthodontic tooth movement
10.3969/j.issn.2095-4344.2017.04.011
- VernacularTitle:正畸牙移动中热休克蛋白70在牙周组织中的表达
- Author:
Jing NIE
;
Han JIANG
;
Zehui LI
;
Xu PAN
;
Chunxia LI
- From:
Chinese Journal of Tissue Engineering Research
2017;21(4):559-563
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Extensive research has been concentrated on the reconstruction of periodontium under orthodontic force. However, there are no reports regarding the expression of heat shock protein 70 (HSP70) in rat periodontium during orthodontic tooth movement. OBJECTIVE:To investigate the expression of HSP70 in rat periodontium during orthodontic tooth movement. METHODS:Rat orthodontic tooth movement models were established using NiTi extension spring with the force of 50 g. The orthodontic periodontium was col ected at 1, 3, 5, 7, 10 and 14 days after exerting force to detect the expression of HSP70. RESULTS AND CONCLUSION:According to immunofluorescence staining, the expression of HSP70 in the periodontal tissues was increased on day 1 after exerting force, and reached the highest level on day 5, then decreased to the initial level on day 14. These results suggest that the expression of HSP70 is evoked by orthodontic force, and it may play a role in periodontal remodeling.
